nios下载失败

有哪位下载nios程序下载失败，出现这种情况吗 请教下最后怎么解决的
Using cable "USB-Blaster [USB-0]", device 1, instance 0x00
Pausing target processor: not responding.
Resetting and trying again: OK
Initializing CPU cache (if present)
OK

Downloading 04000000 ( 0%)assertion "m_state == STATE_DEBUG" failed: file "nios2
debug.cpp", line 1816
C:\altera\10.0\alter\nios2eds\bin\nios2-download: line 601:  5224 Hangup        
          nios2-gdb-server --instance 0 --tcpport none --write-pid ./Debug/nios2
-download.pid Debug/hello_world_0.elf.srec